Assessing Iron Status: Beyond Serum Ferritin and Transferrin Saturation

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Assessing iron status: beyond serum ferritin and transferrin saturation.

The increasing prevalence of multiple comorbidities among anemic patients with chronic kidney disease has made the use of serum ferritin and transferrin saturation more challenging in diagnosing iron deficiency. Because serum ferritin is an acute-phase reactant and because the inflammatory state may inhibit the mobilization of iron from reticuloendothelial stores, the scenario of patients with ...

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Serum ferritin and transferrin saturation in Asians and Pacific Islanders.

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Serum transferrin receptor, serum ferritin and serum transferrin receptor-ferritin index in adults with iron deficiency anaemia.

BACKGROUND Serum Ferritin (SF) and iron both show acute phase responses to inflammation, so iron may fall and ferritin rise independent of the marrow iron store. Bone marrow iron store has been considered the gold standard, but is invasive, painful and expensive and not suitable for everyone. Serum transferrin receptor (sTfR) which is the concentration of the soluble fragment of transferrin rec...

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Dried plasma spot measurements of ferritin and transferrin receptor for assessing iron status.

BACKGROUND Efforts to reduce the high global prevalence of nutritional anemia require the use of both reliable laboratory assays to distinguish iron deficiency from other causes of anemia and cost-effective methods for collection of blood specimens under field conditions. The suitability of using small plasma samples spotted and dried on filter paper for measurements of plasma ferritin and tran...

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Genome-wide admixture and association study of serum iron, ferritin, transferrin saturation and total iron binding capacity in African Americans.

Iron is an essential component of many important proteins and enzymes, including hemoglobin, which is responsible for carrying oxygen to the cells. African Americans (AAs) have a greater prevalence of iron deficiency compared with European Americans. We conducted genome-wide admixture-mapping and association studies for serum iron, serum ferritin, transferrin saturation (SAT) and total iron bin...

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ژورنال

عنوان ژورنال: Clinical Journal of the American Society of Nephrology

سال: 2006

ISSN: 1555-9041,1555-905X

DOI: 10.2215/cjn.01490506